The rs2018736 fibulin-5 polymorphism as a determinant for pelvic organ prolapse: a case-control study.

doi:10.1080/13697137.2024.2327988

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The rs2018736 fibulin-5 polymorphism as a determinant for pelvic organ prolapse: a case-control study.

Climacteric : the journal of the International Menopause Society - 1 Jun 2024

Teixeira Juliana B, Bortolini Maria A T, Silva Rebecca S P, Batista Nilce C, Costa E Silva Carolina L, Allen-Brady Kristina, Castro Rodrigo A

Abstract excerpt

OBJECTIVE: Fibulin-5 is a connective tissue component and may play a role in pelvic organ prolapse (POP) pathogenesis. This study aimed to verify the association of the rs2018736 polymorphism of the fibulin-5 gene with POP in postmenopausal Brazilian women, and to determine the risk factors for POP. METHOD: This observational, cross-sectional, case-control study assessed postmenopausal women with advanced POP...

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PMID: 38533754
DOI: 10.1080/13697137.2024.2327988

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