Article
Pelvic floor disorders: linking genetic risk factors to biochemical changes.
BJU international - 1 Oct 2011
Campeau Lysanne, Gorbachinsky Ilya, Badlani Gopal H, Andersson Karl Erik
Abstract excerpt
Pelvic floor disorders (PFDs) such as stress urinary incontinence (SUI) and pelvic organ prolapse (POP) may share a common pathophysiological process related to pelvic floor tissue laxity and loss of support. We reviewed recent literature on observed biochemical changes in women with SUI and POP, linking them to genetic predisposition. We found that studies of pelvic tissues showed differences between control...
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