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Article

The polymorphisms of extracellular matrix-remodeling genes are associated with pelvic organ prolapse.

International urogynecology journal - 1 Feb 2022

Li Lei, Ma Yidi, Yang Hua, Sun Zhijing, Chen Juan, Zhu Lan

Abstract excerpt

INTRODUCTION AND HYPOTHESIS: Extracellular matrix (ECM) synthesis and metabolism abnormalities may influence the pelvic supporting system and lead to the occurrence and development of pelvic organ prolapse (POP). Genetic polymorphisms of such related genes have been increasingly studied. This study aims to explore the association between the single-nucleotide polymorphisms (SNPs) of genes encoding ECM processing...

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Identifiers

PMID: 34973089
DOI: 10.1007/s00192-021-04917-5
PMCID: PMC8803794

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