Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A.

Journal of thrombosis and haemostasis : JTH - 1 Aug 2014

Eckhardt C L, Astermark J, Nagelkerke S Q, Geissler J, Tanck M W T, Peters M, Fijnvandraat K, Kuijpers T W

Abstract excerpt

BACKGROUND: The development of factor (F) VIII neutralizing alloantibodies (inhibitors) is a major complication of treatment with FVIII concentrates in hemophilia A and the etiology is still poorly understood. The low-affinity Fc gamma receptors (FcγR), which are expressed on immune cells, provid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Formation
Share to DNA Copy Number Variations
Share to Hemophilia A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Cellular

Share to Polymorphism, Single Nucleotide

Share to Receptors, IgG

Source

Identifiers

PMID: 24916518
DOI: 10.1111/jth.12631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24916518-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A.PMID 24916518Read ↗

Polymorphisms in FCGR2A (131H/R) and FCGR2B (232I/T) are associated with the development of inhibitors in Chinese hemophilia A patientsSemantic proximity Read ↗

Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis.Semantic proximity Read ↗

Fcgamma receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: association with clinical symptoms.Semantic proximity Read ↗

Human Fc gamma receptor IIA (FcgammaRIIA) genotyping and association with systemic lupus erythematosus (SLE) in Chinese and Malays in Malaysia.Semantic proximity Read ↗

Association of FcγRIIA-R/H131 polymorphism and systemic lupus erythematosus lupus nephritis risk: A meta-analysis.Semantic proximity Read ↗

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.Semantic proximity Read ↗

Fcgamma receptor IIA H/R131 polymorphism in patients with antiphospholipid antibodies.Semantic proximity Read ↗

Rapid typing of the human Fc gamma receptor IIA polymorphism by polymerase chain reaction amplification with allele-specific primers.Semantic proximity Read ↗

Association between Fc-gamma receptor IIa (CD32) gene polymorphism and malaria susceptibility: a meta-analysis based on 6928 subjects.Semantic proximity Read ↗

Fc gamma RIIa polymorphism: a susceptibility factor for immune complex-mediated lupus nephritis in Brazilian patients.Semantic proximity Read ↗

Genetic diversity in human Fc receptor II for immunoglobulin G: Fc gamma receptor IIA ligand-binding polymorphism.Semantic proximity Read ↗

[Study of polymorphism of Fc gamma IIa receptors in Chilean patients with systemic lupus erythematosus].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.