Rapid typing of the human Fc gamma receptor IIA polymorphism by polymerase chain reaction amplification with allele-specific primers.

doi:10.1046/j.1537-2995.1998.38298193100.x

Back to search

Article

Rapid typing of the human Fc gamma receptor IIA polymorphism by polymerase chain reaction amplification with allele-specific primers.

Transfusion - 1 Feb 1998

Flesch B K, Bauer F, Neppert J

Abstract excerpt

BACKGROUND: The human Fc gamma receptor IIa (Fc gamma RIIa) is expressed in two polymorphic forms, Fc gamma RIIa-H131 and Fc gamma RIIa-R131, that differ by the replacement of histidine by arginine at position 131. This replacement is caused by a single-nucleotide exchange of A-->G. The resulting...

Topics

Alleles
Animals
Antigens, CD
DNA Primers
Humans
Mice
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, IgG

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.