Article
Fcgamma receptor IIA H/R131 polymorphism in patients with antiphospholipid antibodies.
Thrombosis and haemostasis - 1 May 1998
Atsumi T, Caliz R, Amengual O, Khamashta M A, Hughes G R
Abstract excerpt
A role for Fcgamma receptor in the pathophysiology of thrombosis in APS has been hypothesized. The polymorphism of this receptor, FcgammaRIIA H/R131, is associated with the binding affinity for human IgG2 (i.e. FcgammaRIIA-H131 isoform has a higher affinity than FcgammaRIIA-R131). Since anti-beta...
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