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Article

Genetic diversity in human Fc receptor II for immunoglobulin G: Fc gamma receptor IIA ligand-binding polymorphism.

Clinical and diagnostic laboratory immunology - 1 Nov 1994

Reilly A F, Norris C F, Surrey S, Bruchak F J, Rappaport E F, Schwartz E, McKenzie S E

Abstract excerpt

Fc gamma receptors, and in particular genetic variation in these receptors, are important in disorders of hose defense, immunohematologic disease, and systemic autoimmune diseases. We investigated the His-Arg (CAT/CGT) polymorphism at codon 131 of the Fc gamma receptor IIA gene, which influences ligand binding by the receptor. Previously, individuals had been classified phenotypically on the basis of differential...

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Identifiers

PMID: 8556514
DOI: 10.1128/cdli.1.6.640-644.1994
PMCID: PMC368380

Genes

CAT

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Source receipt: pubmed, retrieved 7 Sept 2026.

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