Article
HLA-G 14-bp polymorphism: a possible marker of systemic treatment response in psoriasis vulgaris? Preliminary results of a retrospective study.
Dermatologic therapy - 1 Jan 2000
Borghi Alessandro, Rizzo Roberta, Corazza Monica, Bertoldi Alberto Maria, Bortolotti Daria, Sturabotti Giulia, Virgili Annarosa, Di Luca Dario
Abstract excerpt
Human leukocyte antigen-G (HLA-G) is a nonclassical HLA class I molecule that exerts an immunosuppressive function. A 14-base pair (bp) sequence insertion/deletion (INS/DEL) polymorphism in the exon 8 at the 3' untranslated region (UTR) modifies mRNA stability and protein production and has been...
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