Article
HLA-DQA1 and DQB1 Alleles are Associated with Acitretin Response in Patients with Psoriasis.
Frontiers in bioscience (Landmark edition) - 28 Sept 2022
Zhou Xingchen, He Yijing, Kuang Yehong, Chen Wangqing, Zhu Wu
Abstract excerpt
BACKGROUND: Psoriasis vulgaris is an immune-mediated inflammatory skin disease. Although the pathogenesis of psoriasis is unclear, genetic susceptibility, such as HLA-C*06:02, is believed to be a major risk factor. However, there is a paucity of knowledge regarding the relationship between genetics and the response to systemic treatment of psoriasis. We hypothesized that genetic variations in human leukocyte...
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