Article
Association between Psoriasis and haplotypes of the IgH 3' Regulatory Region 1.
Gene - 30 Aug 2018
D'Addabbo Pietro, Serone Eliseo, Esposito Maria, Vaccari Gabriele, Gargioli Cesare, Frezza Domenico, Bianchi Luca
Abstract excerpt
The association studies of several immune-diseases with the 3' Regulatory Region 1 (3'RR1) increased interest on the role that the region plays in the immune-regulation. The 3'RR1 is a polymorphic region on human chromosome 14q32, acting as a cis-regulative element on the Immunoglobulin constant-gene locus recently considered as super-enhancer. The human 3'RR1 share large sequences with its paralogous 3'RR2, at...
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