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Article

Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort.

Blood - 12 May 2011

Campos Marco, Sun Wei, Yu Fuli, Barbalic Maja, Tang Weihong, Chambless Lloyd E, Wu Kenneth K, Ballantyne Christie, Folsom Aaron R, Boerwinkle Eric, Dong Jing-Fei

Abstract excerpt

von Willebrand factor (VWF) is an essential component of hemostasis and has been implicated in thrombosis. Multimer size and the amount of circulating VWF are known to impact hemostatic function. We associated 78 VWF single nucleotide polymorphisms (SNPs) and haplotypes constructed from those SNPs with VWF antigen level in 7856 subjects of European descent. Among the nongenomic factors, age and body mass index...

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Identifiers

PMID: 21343614
DOI: 10.1182/blood-2010-08-300152
PMCID: PMC3109544

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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