Article
Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.
BMC medical genetics - 19 Sept 2007
Yang Qiong, Kathiresan Sekar, Lin Jing-Ping, Tofler Geoffrey H, O'Donnell Christopher J
Abstract excerpt
BACKGROUND: Increased circulating levels of hemostatic factors as well as anemia have been associated with increased risk of cardiovascular disease (CVD). Known associations between hemostatic factors and sequence variants at genes encoding these factors explain only a small proportion of total phenotypic variation. We sought to confirm known putative loci and identify novel loci that may influence either trait...
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