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Article

Common genetic variants associated with plasma fibrin D-dimer concentration in older European- and African-American adults.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2008

Lange L A, Reiner A P, Carty C L, Jenny N S, Cushman M, Lange E M

Abstract excerpt

BACKGROUND AND OBJECTIVES: D-dimer is a hemostasis marker that reflects ongoing fibrin formation and degradation. There is significant inter-individual and inter-population variability in D-dimer concentration, but whether genetic factors underlie these differences is largely unknown. We hypothesized that common coagulation gene variants contribute to differences in circulating D-dimer concentration. METHODS: The...

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Source

Identifiers

PMID: 18208536
DOI: 10.1111/j.1538-7836.2008.02906.x

Genes

FGG
PLAU
SERPINE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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