Article
Neural Stem Cells Differentiated From iPS Cells Spontaneously Regain Pluripotency
4 Jun 2014
Abstract excerpt
Differentiated somatic cells can be reprogrammed into pluripotent stem cells by transduction of exogenous reprogramming factors. After induced pluripotent stem (iPS) cells are established, exogenous genes are silenced. In the pluripotent state, retroviral genes integrated in the host genome are kept inactive through epigenetic transcriptional regulation. In this study, we tried to determine whether exogenous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
