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Neural Induction and Patterning in Mammalian Pluripotent Stem Cells

1 Jun 2011

Abstract excerpt

Embryonic stem (ES) cells are derived from the inner cell mass (ICM) of blastocyst stage embryos, while induced pluripotent stem (iPS) cells are generated from somatic cells through transient overexpression of defined transcription factors. When transplanted into a preimplantation embryo, ES cells and iPS cells can differentiate into any cell type, including germ cells. Moreover, they can grow in culture...

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PMID: 21495966
DOI: 10.2174/187152711795563958

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