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Direct reprogramming of mouse fibroblasts to neural progenitors

26 Apr 2011

Abstract excerpt

The simple yet powerful technique of induced pluripotency may eventually supply a wide range of differentiated cells for cell therapy and drug development. However, making the appropriate cells via induced pluripotent stem cells (iPSCs) requires reprogramming of somatic cells and subsequent redifferentiation. Given how arduous and lengthy this process can be, we sought to determine whether it might be possible to...

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PMID: 21521790
DOI: 10.1073/pnas.1103113108

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