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Induced Tissue-Specific Stem Cells and Epigenetic Memory in Induced Pluripotent Stem Cells

21 Mar 2018

Abstract excerpt

Induced pluripotent stem (iPS) cells have significant implications for overcoming most of the ethical issues associated with embryonic stem (ES) cells. The pattern of expressed genes, DNA methylation, and covalent histone modifications in iPS cells are very similar to those in ES cells. However, it has recently been shown that, following the reprogramming of mouse/human iPS cells, epigenetic memory is inherited...

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PMID: 29561778
DOI: 10.3390/ijms19040930

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