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μHigh resolution-magic-angle spinning NMR spectroscopy for metabolic phenotyping of Caenorhabditis elegans.

Analytical chemistry - 17 Jun 2014

Wong Alan, Li Xiaonan, Molin Laurent, Solari Florence, Elena-Herrmann Bénédicte, Sakellariou Dimitris

Abstract excerpt

Analysis of model organisms, such as the submillimeter-size Caenorhabditis elegans, plays a central role in understanding biological functions across species and in characterizing phenotypes associated with genetic mutations. In recent years, metabolic phenotyping studies of C. elegans based on (1)H high-resolution magic-angle spinning (HR-MAS) nuclear magnetic resonance (NMR) spectroscopy have relied on the...

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PMID: 24897622
DOI: 10.1021/ac501208z

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