Article
Cross-platform comparison of Caenorhabditis elegans tissue extraction strategies for comprehensive metabolome coverage.
Analytical chemistry - 15 May 2011
Geier Florian M, Want Elizabeth J, Leroi Armand M, Bundy Jacob G
Abstract excerpt
The nematode Caenorhabditis elegans is widely used as a model organism in many areas of the life sciences. Metabolite profiling (metabolomics/metabonomics) is a powerful means of assigning phenotypes to experimentally perturbed C. elegans samples (e.g., mutants, RNAi, or chemical treatments). Tissue extraction is a key step, and high-quality and reproducible extractions are essential to the success of...
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