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Article

CD86 +1057G/A polymorphism and risk of chronic immune thrombocytopenia.

Autoimmunity - 1 Nov 2014

Wu Pin, Wang Zhi, Lu Shiyun, Zhao Xiaohong

Abstract excerpt

The G to A transition at position +1057 single nucleotide polymorphism site in CD86 gene results in the alanine to threonine substitution, which further affects the antigen-presenting cells' signal transduction. Thus, the purpose of this study was to determine the association between CD86 +1057G/A polymorphism and the risk for chronic immune thrombocytopenia (cITP). The CD86 +1057G/A polymorphism in 158 cITP...

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Identifiers

PMID: 24897540
DOI: 10.3109/08916934.2014.921813

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