Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD86 gene variants and susceptibility to pancreatic cancer.

Journal of cancer research and clinical oncology - 1 Dec 2012

Xiang Honggang, Zhao Wei, Sun Yanping, Qian Winnie, Xing Junjie, Zhou Yujia, Yao Jun, Xu Jian, Wang Yi, Yao Houshan, Hu Zhiqian

Abstract excerpt

BACKGROUND: Pancreatic cancer is one of the most lethal cancers worldwide. CD86 (B7-2) is a costimulatory molecule on antigen-presenting cells and plays critical roles in tumor immunity. It has been reported that polymorphisms in CD86 gene can be involved in the development of various cancers. Here, we investigated the association of two CD86 polymorphisms, +1057G/A (rs1129055) and +2379G/C (rs17281995), with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigen-Presenting Cells
Share to Asian People
Share to B7-2 Antigen
Share to Carcinoma, Pancreatic Ductal
Share to Gene Frequency
Share to Haplotypes
Share to Odds Ratio
Share to Pancreatic Neoplasms

Source

Identifiers

PMID: 22821131
DOI: 10.1007/s00432-012-1289-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD86 gene variants and susceptibility to pancreatic cancer.PMID 22821131Read ↗

CD86 +1057 G/A polymorphism and the risk of colorectal cancer.Semantic proximity Read ↗

Distinct role of CD86 polymorphisms (rs1129055, rs17281995) in risk of cancer: evidence from a meta-analysis.Semantic proximity Read ↗

Genome-wide association study of pancreatic cancer in Japanese population.Semantic proximity Read ↗

CD86 + 1057G/A polymorphism and susceptibility to osteosarcoma.Semantic proximity Read ↗

Case-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan.Semantic proximity Read ↗

Cytotoxic T-lymphocyte antigen-4 +49G/A polymorphism and susceptibility to pancreatic cancer.Semantic proximity Read ↗

Association between rs9904341 G<C gene polymorphism and susceptibility to pancreatic cancer in a Chinese population.Semantic proximity Read ↗

Genetic polymorphisms in inflammatory genes and pancreatic cancer risk: a two-phase study on more than 14 000 individuals.Semantic proximity Read ↗

CD24 and APC Genetic Polymorphisms in Pancreatic Cancers as Potential Biomarkers for Clinical Outcome.Semantic proximity Read ↗

Functional variants in cell death pathway genes and risk of pancreatic cancer.Semantic proximity Read ↗

Association between ABO gene polymorphism (rs505922) and cancer risk: a meta-analysis.Semantic proximity Read ↗

Rs1347093 regulates microRNA-216/-217 expression and is associated with pancreatic cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.