Article
CD86 + 1057G/A polymorphism and susceptibility to osteosarcoma.
DNA and cell biology - 1 Nov 2011
Wang Wen, Song Haihan, Liu Jie, Song Bao, Cao Xuecheng
Abstract excerpt
CD86 (B7-2), one of the costimulatory molecules on antigen-presenting cells, plays essential roles not only in autoimmunity and transplantation but also in tumor immunity. CD86 + 1057G/A polymorphism (rs1129055) is associated with various diseases. The objective of this study was to investigate the association between CD86 + 1057G/A polymorphism and susceptibility to osteosarcoma in a Chinese population. The...
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