Article
CD86 +1057G>A polymorphism and susceptibility to acute kidney allograft rejection.
Iranian journal of kidney diseases - 1 Jul 2011
Krichen Henda, Sfar Imen, Bardi Rafika, Ben Abdallah Taieb, Jendoubi-Ayed Salwa, Ben Aleya Walid, Makhlouf Mouna, Ben Rhomdhane Thouraya, Aouadi Houda, Abderrahim Ezzeddine, Ayed Khaled, Gorgi Yousr
Abstract excerpt
INTRODUCTION: CD86 is a costimulatory molecule that participates in the regulation of T-cell lymphocytes activation. Thus, we examined a genetic marker on the CD86 gene in kidney transplant outcome. MATERIALS AND METHODS: In our retrospective study, 168 kidney allograft recipients were genotyped by direct sequencing. Patients were classified into 2 groups of 29 human leukocyte antigen (HLA)-identical haplotype...
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