CD86 +1057G/A polymorphism and susceptibility to Ewing's sarcoma: a case-control study.

doi:10.1089/dna.2011.1370

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Article

CD86 +1057G/A polymorphism and susceptibility to Ewing's sarcoma: a case-control study.

DNA and cell biology - 1 Apr 2012

Wang Jian, Zhou Yujia, Feng Dapeng, Yang Haitao, Li Feng, Cao Qianlai, Wang An, Xing Fei

Abstract excerpt

The development of Ewing's sarcoma (ES) is a complex process resulting from interplay between mutations in oncogenes and tumor suppressors, host susceptibility factors, and cellular context. CD86 (B7-2) may affect cancer susceptibility by modulating T cell response. CD86 +1057G/A polymorphism (rs1129055) has been reported to be associated with various diseases. Here, we investigated the association between CD86...

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PMID: 21870962
DOI: 10.1089/dna.2011.1370

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