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Article

CD86 +1057 G/A polymorphism and the risk of colorectal cancer.

DNA and cell biology - 1 Jul 2010

Pan Xin-Min, Gao Lin-Bo, Liang Wei-Bo, Liu Yun, Zhu Yi, Tang Ming, Li Ying-Bi, Zhang Lin

Abstract excerpt

CD86 (B7-2), one of the costimulatory molecules on antigen-presenting cells, plays essential roles not only in autoimmunity and transplantation but also in tumor immunity. The purpose of this study was to investigate whether CD86 gene polymorphism was involved in predisposing an individual to colorectal cancer (CRC). The CD86 +1057 G/A polymorphism was genotyped by performing polymerase chain reaction-restriction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20380573
DOI: 10.1089/dna.2009.1003

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