Article
TNF-α promoter single nucleotide polymorphisms and haplotypes associate with susceptibility of immune thrombocytopenia in Chinese adults.
Human immunology - 1 Sept 2014
Wang Ning, Li Gui Ning, Wang Xiao Bei, Liang Tao, Hu Lihua
Abstract excerpt
OBJECTIVE: Tumor necrosis factor-alpha (TNF-α) participates as a candidate susceptibility factor for immune thrombocytopenia (ITP). This study attempted to investigate the association between five single nucleotide polymorphisms (SNPs) spanning the TNF-α promoter and the susceptibility of primary ITP in Chinese Han adults. METHODS: In 215 adult primary ITP patients and 206 healthy controls, SNPs were detected by...
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