Correlation between interleukin-18 promoter -607C/A polymorphism and susceptibility to ischemic stroke.

doi:10.1590/1414-431X20132850

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Article

Correlation between interleukin-18 promoter -607C/A polymorphism and susceptibility to ischemic stroke.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jun 2013

Lu Jian-xia, Lu Zhong-qian, Zhang Shao-lan, Zhi Juan, Chen Zheng-ping, Wang Wan-xiang

Abstract excerpt

Single nucleotide polymorphisms in the promoter region of interleukin-18 (IL-18), an inflammatory cytokine, have been linked to susceptibility to many diseases, including cancer and immune dysfunction. Here, we explored the potential association between the IL-18 -607C/A (rs1946518) promoter region polymorphism and susceptibility to ischemic stroke (IS). This locus was amplified from peripheral blood samples of...

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Identifiers

PMID: 23739747
DOI: 10.1590/1414-431X20132850
PMCID: PMC3854443

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