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Article

Development of gene-switch transgenic mice that inducibly express transforming growth factor β1 in the epidermis

20 Jul 1999

Abstract excerpt

Previous attempts to establish transgenic mouse models to study the functions of transforming growth factor beta1 (TGFbeta1) in the skin revealed controversial roles for TGFbeta1 in epidermal growth (inhibition vs. stimulation) and resulted in neonatal lethality in one instance. To establish a viable transgenic model for studying functions of TGFbeta1 in the skin, we have now developed transgenic mice, which...

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PMID: 10411901
DOI: 10.1073/pnas.96.15.8483

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Source receipt: pubmed, retrieved 7 Sept 2026.

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