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Article

A genetic association study detects haplotypes associated with obstructive heart defects.

Human genetics - 1 Sept 2014

Li Ming, Cleves Mario A, Mallick Himel, Erickson Stephen W, Tang Xinyu, Nick Todd G, Macleod Stewart L, Hobbs Charlotte A

Abstract excerpt

The development of congenital heart defects (CHDs) involves a complex interplay between genetic variants, epigenetic variants, and environmental exposures. Previous studies have suggested that susceptibility to CHDs is associated with maternal genotypes, fetal genotypes, and maternal-fetal genotype (MFG) interactions. We conducted a haplotype-based genetic association study of obstructive heart defects (OHDs),...

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Identifiers

PMID: 24894164
DOI: 10.1007/s00439-014-1453-1
PMCID: PMC4313870

Genes

CBS
MGMT
MTHFS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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