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Article

Detecting maternal-fetal genotype interactions associated with conotruncal heart defects: a haplotype-based analysis with penalized logistic regression.

Genetic epidemiology - 1 Apr 2014

Li Ming, Erickson Stephen W, Hobbs Charlotte A, Li Jingyun, Tang Xinyu, Nick Todd G, Macleod Stewart L, Cleves Mario A

Abstract excerpt

Nonsyndromic congenital heart defects (CHDs) develop during embryogenesis as a result of a complex interplay between environmental exposures, genetics, and epigenetic causes. Genetic factors associated with CHDs may be attributed to either independent effects of maternal or fetal genes, or the intergenerational interactions between maternal and fetal genes. Detecting gene-by-gene interactions underlying complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24585533
DOI: 10.1002/gepi.21793
PMCID: PMC4043210

Genes

GCLC
GSTM3
RFC1
AHCYL2
GSTA1
MTRR
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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