Article
Association of Maternal Betaine-Homocysteine Methyltransferase (BHMT) and BHMT2 Genes Polymorphisms with Congenital Heart Disease in Offspring.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2023
Luo Manjun, Wang Tingting, Huang Peng, Zhang Senmao, Song Xinli, Sun Mengting, Liu Yiping, Wei Jianhui, Shu Jing, Zhong Taowei, Chen Qian, Zhu Ping, Qin Jiabi
Abstract excerpt
To systematically explore the association of single nucleotide polymorphisms (SNPs) of maternal BHMT and BHMT2 genes with the risk of congenital heart disease (CHD) and its three subtypes including atrial septal defect (ASD), ventricular septal defect (VSD), and patent ductus arteriosus (PDA) in offspring. A hospital-based case-control study involving 683 mothers of CHD children and 740 controls was performed....
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