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Article

Exploring the functional residues in a flavin-binding fluorescent protein using deep mutational scanning.

PloS one - 1 Jan 2014

Shin HyeonSeok, Cho Yoobok, Choe Dong-hui, Jeong Yujin, Cho Suhyung, Kim Sun Chang, Cho Byung-Kwan

Abstract excerpt

Flavin mononucleotide (FMN)-based fluorescent proteins are versatile reporters that can monitor various cellular processes in both aerobic and anaerobic conditions. However, the understanding of the role of individual amino acid residues on the protein function has been limited and has restricted the development of better functional variants. Here we examine the functional amino acid residues of Escherichia coli...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24887409
DOI: 10.1371/journal.pone.0097817
PMCID: PMC4041573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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