Article
Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients.
BMC cancer - 24 May 2014
Miao Liyun, Wang Yongsheng, Zhu Suhua, Shi Minke, Li Yan, Ding Jingjing, Yang Jun, Ye Qing, Cai Hourong, Zhang Deping, Liu Hongbing, Song Yong
Abstract excerpt
BACKGROUND: Although many of the recently approved genomically targeted therapies have improved outcomes for patients in non-small-cell lung cancer (NSCLC) with lung adenocarcinoma, little is known about the genomic alterations that drive lung squamous cell cancer (SCC) and development of effective targeted therapies in lung SCC is a promising area to be further investigated. Discoidin domain receptor 2 (DDR2),...
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