Article
Mutational Landscape of DDR2 Gene in Lung Squamous Cell Carcinoma Using Next-generation Sequencing.
Clinical lung cancer - 1 Mar 2018
Ricordel Charles, Lespagnol Alexandra, Llamas-Gutierrez Francisco, de Tayrac Marie, Kerjouan Mallorie, Fievet Alice, Hamdi-Rozé Houda, Aliouat Amyrat, Desrues Benoit, Mosser Jean, Léna Hervé
Abstract excerpt
BACKGROUND: Lung cancer represents the leading cause of cancer-related death worldwide. Despite great advances in lung cancer management with the recent emergence of molecular targeted therapies for non-squamous non-small-cell lung cancer, no dramatic improvements have been achieved in lung squamous cell carcinoma (SCC). Mutations in discoidin domain receptor 2 (DDR2) gene were recently identified as promising...
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