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Article

Genetic insight and therapeutic targets in squamous-cell lung cancer.

Oncogene - 15 Nov 2012

Sos M L, Thomas R K

Abstract excerpt

Squamous-cell lung cancer is one of the most prevalent subtypes of lung cancer worldwide and its pathogenesis is closely linked with tobacco exposure. Unfortunately, squamous-cell lung cancer patients do not benefit from major advances in the development of targeted therapeutics such as epidermal growth factor receptor (EGFR) inhibitors or anaplastic lymphoma kinase (ALK) inhibitors that show exquisite activity...

Read the complete abstract on PubMed

Topics

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Share to EML4 gene
Share to Lung Neoplasms
Share to Molecular Targeted Therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms, Squamous Cell

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Receptor Protein-Tyrosine Kinases

Share to Receptors, Mitogen

Source

Identifiers

PMID: 22266863
DOI: 10.1038/onc.2011.640

Genes

ALK
EGFR
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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