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Article

Sensitive methods for detection of the S768R substitution in exon 18 of the DDR2 gene in patients with central nervous system metastases of non-small cell lung cancer.

Medical oncology (Northwood, London, England) - 1 Oct 2014

Nicoś Marcin, Powrózek Tomasz, Krawczyk Paweł, Jarosz Bożena, Pająk Beata, Sawicki Marek, Kucharczyk Krzysztof, Trojanowski Tomasz, Milanowski Janusz

Abstract excerpt

Discoidin death receptor 2 (DDR2) receptor belongs to a DDR family that shows a tyrosine kinase activity. The somatic mutations in DDR2 gene, reported in non-small cell lung cancer (NSCLC), are involved in up-regulation of cells' migration, proliferation and survival. A S768R substitution in DDR2...

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Source

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Identifiers

PMID: 25173530
DOI: 10.1007/s12032-014-0176-4
PMCID: PMC4180903

Genes

DDR2
KRAS
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25173530-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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