Article
Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma.
British journal of cancer - 12 Mar 2007
Ford C E, Lau S K, Zhu C Q, Andersson T, Tsao M S, Vogel W F
Abstract excerpt
The discoidin domain receptors, (DDR)1 and DDR2, have been linked to numerous human cancers. We sought to determine expression levels of DDRs in human lung cancer, investigate prognostic determinates, and determine the prevalence of recently reported mutations in these receptor tyrosine kinases. Tumour samples from 146 non-small cell lung carcinoma (NSCLC) patients were analysed for relative expression of DDR1...
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