Article
Functional analysis of Discoidin domain receptor 2 mutation and expression in squamous cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2017
Kobayashi-Watanabe Naomi, Sato Akemi, Watanabe Tatsuro, Abe Tomonori, Nakashima Chiho, Sueoka Eisaburo, Kimura Shinya, Sueoka-Aragane Naoko
Abstract excerpt
OBJECTIVES: Discoidin domain receptor (DDR) 2 mutations have recently been reported to be candidate targets of molecular therapy in lung squamous cell carcinoma (SQCC). However, the status of DDR2 expression and mutations, as well as their precise roles in lung SQCC, have not been clarified. We here report DDR2 mutation and expression status in clinical samples and its role of lung SQCC. MATERIALS AND METHODS: We...
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