Article
On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis.
BMC genomics - 14 May 2014
Peterson Roseann E, Maes Hermine H, Lin Peng, Kramer John R, Hesselbrock Victor M, Bauer Lance O, Nurnberger John I, Edenberg Howard J, Dick Danielle M, Webb Bradley T
Abstract excerpt
BACKGROUND: As the architecture of complex traits incorporates a widening spectrum of genetic variation, analyses integrating common and rare variation are needed. Body mass index (BMI) represents a model trait, since common variation shows robust association but accounts for a fraction of the heritability. A combined analysis of single nucleotide polymorphisms (SNP) and copy number variation (CNV) was performed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.