Article
Copy number variations associated with obesity-related traits in African Americans: a joint analysis between GENOA and HyperGEN.
Obesity (Silver Spring, Md.) - 1 Dec 2012
Zhao Wei, Wineinger Nathan E, Tiwari Hemant K, Mosley Thomas H, Broeckel Ulrich, Arnett Donna K, Kardia Sharon L R, Kabagambe Edmond K, Sun Yan V
Abstract excerpt
Obesity is a highly heritable trait and a growing public health problem. African Americans (AAs) are a genetically diverse, yet understudied population with a high prevalence of obesity (BMI >30 kg/m(2)). Recent studies based upon single-nucleotide polymorphisms (SNPs) have identified genetic markers associated with obesity. However, a large proportion of the heritability of obesity remains unexplained. Copy...
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