Article
Estrogen receptor polymorphisms and the risk of endometrial cancer.
BJOG : an international journal of obstetrics and gynaecology - 1 Jul 2009
Ashton K A, Proietto A, Otton G, Symonds I, McEvoy M, Attia J, Gilbert M, Hamann U, Scott R J
Abstract excerpt
OBJECTIVE: There is evidence that estrogens and some of their metabolites are involved in endometrial cancer pathogenesis. As estrogens mediate their effects via the estrogen receptors, ESR1 and ESR2, the objective of this investigation was to determine whether six single nucleotide polymorphisms (SNPs) in these two genes were over-represented in a population of endometrial cancer patients compared with a healthy...
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