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Article

Functional characterization of a genetic polymorphism in the promoter of the ESR2 gene.

Hormones & cancer - 1 Apr 2012

Philips Santosh, Richter Alexandra, Oesterreich Steffi, Rae James M, Flockhart David A, Perumal Narayanan B, Skaar Todd C

Abstract excerpt

The ESR2 gene encodes the estrogen receptor beta protein. Several studies have shown that genetic variants in the ESR2 gene are associated with a variety of clinical phenotypes. However, very little is known about the functional significance of ESR2 genetic variants. We used a bioinformatics approach to identify regions of the ESR2 promoter that is evolutionarily conserved across the genomes of several species....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21979797
DOI: 10.1007/s12672-011-0086-2
PMCID: PMC3402208

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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