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ESR2 gene variants (rs1256049, rs4986938, and rs1256030) and their association with breast cancer risk.

PeerJ - 1 Jan 2022

Gallegos-Arreola Martha Patricia, Zúñiga-González Guillermo M, Figuera Luis E, Puebla-Pérez Ana María, Márquez-Rosales María Guadalupe, Gómez-Meda Belinda Claudia, Rosales-Reynoso Mónica Alejandra

Abstract excerpt

Background: Variants of the estrogen receptor b (ESR2) gene have been associated with different types of cancer. However, these associations have been inconsistent. We genotyped the ESR2 variants (rs1256049, rs4986938, and rs1256030) in breast cancer (BC) patients and in healthy women. Results: The variants rs1256049 and rs4986938 in the ESR2 gene were not associated with risk susceptibility in BC patients....

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Breast Neoplasms
Case-Control Studies
Estrogen Receptor beta
Polymorphism, Single Nucleotide
Risk Factors

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Open in PubMed Open full text

Identifiers

PMID: 35573183
DOI: 10.7717/peerj.13379
PMCID: PMC9104083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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