Article
Estrogen receptor beta gene polymorphisms and susceptibility to uterine fibroids.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2010
Fischer Claudia, Juhasz-Boess Ingolf, Lattrich Claus, Ortmann Olaf, Treeck Oliver
Abstract excerpt
Uterine fibroids are the most common benign tumors of the female genital tract. Steroid hormones, especially estradiol and progesterone, play an important role in the pathobiology of this frequent disease. Recent studies suggested that both expression levels and polymorphisms of estrogen receptor (ER) alpha and beta might affect development of uterine fibroids. In this study, we tested whether single nucleotide...
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