Article
Genetic polymorphisms in the estrogen receptor beta (ESR2) gene and the risk of epithelial ovarian carcinoma.
Cancer causes & control : CCC - 1 Feb 2009
Lurie Galina, Wilkens Lynne R, Thompson Pamela J, McDuffie Katharine E, Carney Michael E, Terada Keith Y, Goodman Marc T
Abstract excerpt
Ovarian cancer is influenced by exogenous and endogenous estrogens as suggested by experimental and epidemiological evidence. Estrogen receptor beta is a predominant estrogen receptor in the normal ovary. Polymorphisms in the estrogen receptor beta gene (ESR2) might influence epithelial ovarian risk through regulation of cell proliferation and apoptosis. This population-based case-control study included 313 women...
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