Article
Novel insights into thyroid hormones from the study of common genetic variation.
Nature reviews. Endocrinology - 1 Apr 2009
Dayan Colin M, Panicker Vijay
Abstract excerpt
Effects of thyroid hormones in individual tissues are determined by many factors beyond their serum levels, including local deiodination and expression and activity of thyroid hormone transporters. These effects are difficult to examine by traditional techniques, but a novel approach that exploits the existence of common genetic variants has yielded new and surprising insights. Convincing evidence indicates a...
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