Article
Genetic variation in PLCE1 is associated with gastric cancer survival in a Chinese population.
Journal of gastroenterology - 1 Nov 2011
Luo Dewei, Gao Yan, Wang Shizhi, Wang Meilin, Wu Dongmei, Wang Wei, Xu Ming, Zhou Jianwei, Gong Weida, Tan Yongfei, Zhang Zhengdong
Abstract excerpt
BACKGROUND: Two genome-wide association studies on gastric cancer showed a previously unknown gastric cancer susceptible locus in PLCE1 at 10q23. We hypothesized that the single nucleotide polymorphism (SNP) rs2274223 A/G is associated with the survival rate of gastric cancer. METHODS: We genotyped the above SNP in 940 gastric cancer patients to investigate the association between the polymorphism and gastric...
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