Article
Binding of ArgTX-636 in the NMDA receptor ion channel.
Journal of molecular biology - 16 Jan 2015
Poulsen Mette H, Andersen Jacob, Christensen Rune, Hansen Kasper B, Traynelis Stephen F, Strømgaard Kristian, Kristensen Anders Skov
Abstract excerpt
The N-methyl-d-aspartate receptors (NMDARs) constitute an important class of ligand-gated cation channels that are involved in the majority of excitatory neurotransmission in the human brain. Compounds that bind in the NMDAR ion channel and act as blockers are use- and voltage-dependent inhibitor...
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