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Article

Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating.

The Journal of general physiology - 1 Jun 2007

Sobolevsky Alexander I, Prodromou Michael L, Yelshansky Maria V, Wollmuth Lonnie P

Abstract excerpt

N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ion channels that contribute to fundamental physiological processes such as learning and memory and, when dysfunctional, to pathophysiological conditions such as neurodegenerative diseases, stroke, and mental illness. NMDARs are obligate heteromultimers typically composed of NR1 and NR2 subunits with the different subunits underlying the functional...

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Identifiers

PMID: 17504910
DOI: 10.1085/jgp.200609718
PMCID: PMC2151626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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