Article
Genetic regulation of mouse liver metabolite levels.
Molecular systems biology - 23 May 2014
Ghazalpour Anatole, Bennett Brian J, Shih Diana, Che Nam, Orozco Luz, Pan Calvin, Hagopian Raffi, He Aiqing, Kayne Paul, Yang Wen-pin, Kirchgessner Todd, Lusis Aldons J
Abstract excerpt
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of 104 inbred and recombinant inbred strains. We find that metabolites exhibit a wide range of variation, as has been previously observed with metabolites in blood serum. Using...
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